CONSIDERATION OF “THE 3 R’s” Background: Principle 3 of the U.S. Government Principles for the Utilization and Care of Vertebrate Animals Used in Testing, Research, and Training states that “animals selected for a procedure should be of an appropriate species and quality and the minimum number required to obtain valid results. Methods such as mathematical models, computer simulation, and in … Read More
Notification of Change in ARC Review and Approval of Collaborative Research Between UCLA and the VAGLAHS
On April 1, 2005, the Memorandum of Understanding Regarding Care and Use of Laboratory Animal Subjects between UCLA and the VA Greater Los Angeles Healthcare System (VAGLAHS) was revised to eliminate the requirement for dual Animal Research Committee (ARC) and Institutional Animal Care and Use Committee (IACUC) review for most collaborative projects between UCLA and VAGLAHS. This change is applicable … Read More
Reporting Serious and Continuing Noncompliance to the NIH Office of Laboratory Animal Welfare (OLAW)
PHS Policy IV.F.3 requires that the ARC, through the Institutional Official, promptly provide OLAW with a full explanation of the circumstances and actions taken with respect to: (a) any serious or continuing noncompliance with PHS Policy; (b) any serious deviation from the provisions of the Guide for the Care and Use of Laboratory Animals; or (c) any suspension of an … Read More
Estimating the Number of Animals
The ARC guidance on Estimating the Number of Animals has been revised to include resources that investigators may find helpful in determining animal numbers for their research applications.
New Resource for Investigators: How to Write an Application Involving Research Animals
Developed by the National Institute of Allergy and Infectious Diseases (NIAID), in conjunction with the NIH Office of Laboratory Animal Welfare (OLAW), this tutorial provides a step by step guide to the preparation of an application and covers such topics as considering alternatives, obtaining assurances and Institutional Animal Care and Use Committee (IACUC) approval, Just-In-Time processes, NIH review of animal … Read More
Procedures for Reporting Procurement of Animals Through Non-Traditional Vendors/Sources
In order to comply with the USDA Animal Welfare Act Regulations (AWARs) and the PHS Policy on Humane Care and Use of Laboratory Animals (PHS Policy), all ARC protocols must specify and include a rationale for the number of animals that will be used in the study. In order to ensure that the number of animals is limited to that … Read More
Resources & Guidance
Information on Material Safety Data Sheets (MSDS): Cal/OSHA Requirements and How to Obtain an MSDS Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research, Institute for Laboratory Animal Research (ILAR), National Academy of Sciences Frequently Asked Questions About the PHS Policy on Humane Care and Use of Laboratory Animals, NIH Office of Laboratory Animal Welfare (OLAW)
Animal Welfare Act Standards to Be Applied to International Carriers
USDA Press Release issued 10/9/03
USDA Amends Regulations Regarding Possession and Use of Select Biological Agents and Toxins
USDA Press Release issued 11/3/03
Behavioral Testing Core Provides Services and Expertise to UCLA Researchers
The Behavioral Testing Core is a multidisciplinary core located in the UCLA Psychology Department that is available to all UCLA researchers interested in the determination of behavioral phenotypes in different rodent strains. The Core provides facilities and expertise in the design, implementation, and analysis of behavioral experiments and offers assistance to investigators in preparing animal research protocols for submission to … Read More