3Rs Pilot Studies Call for Proposals – Deadline for Submission April 25, 2014

The Office of Animal Research Oversight is pleased to announce the Spring 2014 3Rs funding opportunity, provided by the Office of the Vice Chancellor for Research. Aim of Award: The aim of the program is to promote and support pilot studies designed to replace the use of animals in research, reduce the numbers of animals necessary, or refine methods to … Read More

New Policy on Breeding Colony Management

The ARC has recently approved a new Policy on Breeding Colony Management; the updated Policy is available at the Breeding Colony Management web page. This Policy provides important information about minimum space requirements, harem breeding, and extended weaning periods, and supersedes the long-standing ARC Policy on Extended Weaning Periods. Please contact the Office of Animal Research Oversight at 310-206-6308 or … Read More

ARC POLICY UPDATE: Tissue Collection for DNA Extraction for Genotyping in Rodents

The ARC Policy on Tissue Collection for DNA Extraction for Genotyping in Rodents (formerly Tissue Collection for DNA Extraction for Genotyping in Mice) has recently been revised; the updated Policy is available at the Tissue Collection for DNA Extraction for Genotyping in Rodents web page. The main change pertains to use of anesthesia for ear punching/snipping. As noted in the … Read More

Office of Animal Research Oversight (OARO) 2013-2014 Winter Holiday Closure

The Office of Animal Research Oversight (OARO) will observe UCLA’s 2013-2014 Winter Holiday Closure. OARO will be closed beginning Saturday, December 21, 2013 and will reopen on Thursday, January 2, 2014. During this time, OARO will not process applications for review or approval and will be unavailable via phone and email. Similarly, the Chancellor’s Animal Research Committee (ARC) will not … Read More

AVMA Guidelines for the Euthanasia of Animals – Confirmation of Death

The updated AVMA Guidelines for the Euthanasia of Animals: 2013 Edition emphasizes the need to confirm death following non-physical methods of euthanasia (i.e., CO2, anesthetic overdose). If critical organs (i.e., brain, heart or lungs) are harvested immediately after euthanasia, this is considered acceptable in lieu of a confirmatory method. Confirmatory methods for commonly used species include the following: Mice cervical … Read More

ARC Policy Update: Tumor Development in Rodents

The ARC Policy on Tumor Development in Rodents has recently been revised; the updated Policy is available on the Tumor Development in Rodents web page. An important change to the policy pertains to the use of tumor size limits. Previously, the ARC required euthanasia if tumor burden exceeded 1.5 cm in mice or 2.5 cm in rats, with exceptions to these … Read More

AVMA Guidelines for the Euthanasia of Animals

The American Veterinary Medical Association (AVMA) has released the “AVMA Guidelines for the Euthanasia of Animals: 2013 Edition” as an update to the 2007 Guidelines on Euthanasia. This is the 8th edition (1963, 1972, 1978, 1986, 1993, 2000, 2007 and 2013) that the AVMA has published, and builds upon previous editions. An Executive Summary details substantive changes to the Guidelines. … Read More

Laboratory Disaster Plan for Animal Users

On December 31, 2012, the US Department of Agriculture Animal and Plant Health Inspection Service (APHIS) published a final rule that requires all dealers, exhibitors, intermediate handlers, carriers, research facilities, and other entities regulated by the Agency under the Animal Welfare Act (AWA), to take additional steps to better prepare for potential disaster situations. Registered entities are required to develop … Read More

UPDATE: Resources for Animal Research

The Resources for Animal Research page has been updated to include a section on Guidelines for Wildlife Research. Visit our Resources for Animal Research web page for links to the following Guidelines: Guidelines to the Use of Wild Birds in Research Guidelines of the American Society of Mammalogists for the Use of Wild Mammals in Research Guidelines for the Use … Read More

Suggestions and Reminders About the ARC Review Process

ARC Protocol Expiration: Federal regulations require that animal activities be conducted only under an IACUC (ARC) approved protocol. As such, a lapse in ARC approval for ongoing research is a serious matter that must be avoided. You may not conduct animal activities following a lapse in ARC approval, and any costs incurred to maintain your animals during the lapse must … Read More